|
|
هشتمین سمینار دوسالانه کمومتریکس ایران
|
|
|
| عنوان فارسی |
|
|
| چکیده فارسی مقاله |
|
|
| کلیدواژه‌های فارسی مقاله |
|
|
| عنوان انگلیسی |
Experimental design optimization usage in pathogen detection utilizing green-synthesized re-generable nanocomposite |
|
| چکیده انگلیسی مقاله |
One urgent need for global health, is fast detection of pathogens [1]. A rapid detection assay utilizing synthesized magnetic Ag/Fe3O4/Chitosan (Ag@IO@CS) nanocomposite, was developed for efficient preconcentration and fluorometric determination of trace amounts of gram negative bacteria via SPE method. Cinnamon as a bio reluctant and capping agent was used in the green synthesis procedure [2]. Prepared nanocomposite w::::as char::::acterized by TEM, FTIR and XRD measurements. The fluorescence intensity gradually increased by the prepared nanosensor as E. coli concentration increased from 10 to 104 CFU mL−1 (Fig. 1). Herein we utilized the robust design parameter optimization in the laboratory experiment for effective sensing of bacteria. A 54 design using central composite (CCD) based response surface methodology (RSM) was applied to accommodate the four significant factors as pH, solvent, time of adsorption and time of desorption of bacteria (Fig.2). All in all, preference physical and chemical properties of the prepared nanocomposite besides magnetic separation capability and simultaneous optimization advantages make this nanobiosensor excellent scaffolds for the construction of the unique probe for gram negative pathogen. |
|
| کلیدواژه‌های انگلیسی مقاله |
Central composite design (CCD)، Pathogen nanobiosensor، Ag/Fe3O4/Chitosan composite |
|
| نویسندگان مقاله |
| رامین زیباسرشت
| راضیه موسوی
|
|
| نشانی اینترنتی |
http://chemo2021.modares.ac.ir/browse.php?a_code=A-10-129-1&slc_lang=fa&sid=1 |
| فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
| کد مقاله (doi) |
|
| زبان مقاله منتشر شده |
fa |
| موضوعات مقاله منتشر شده |
|
| نوع مقاله منتشر شده |
|
|
|
|
برگشت به:
صفحه اول پایگاه |
دوره مرتبط |
کنفرانس مرتبط |
فهرست کنفرانس ها
|
